A great joint formula combing MSM with Glucosamine Hydrochloride. Some researchers believe the HCI form of glucosamine is preferable because its smaller molecular size enables it to penetrate better. Although still not as well studied as glucosamine sulfate, recent studies validate it as a very effective form.

MSM (Methylsulfonylmethane, also known as dimethylsulfohone) is a biologically active sulfur compound found throughout the plant and animal kingdoms. Because MSM is readily bio-available and easily assimilated by the body, it plays a key role in both synthesizing numerous sulfur-containing proteins crucial to the proper functioning of the body, and regulating many normal biochemical processes. It helps to alleviate the pain and discomfort of a variety of health conditions, including allergies, gastrointestinal upset, arthritis and joint inflammation, parasitic infection, skin problems, lung disorder, and even snoring. MSM has been clinically proven to provide an average of 82% improvement in pain for sufferers of degenerative joint disease after six weeks of daily use. And there is impressive evidence showing that MSM is safe and non-toxic.

Glucosamine is an amino sugar critical to the integrity of joint tissues. Glucosamine is its best-studied form, officially recognized as an aid to osteoarthritis with the national health organizations of over 100 countries as well as with the World Health Organization. It is a primary constituent of proteoglycans, which are used by the body to form articular cartilage. It stimulates the synthesis of cartilage components so that joints can be repaired. Further, Glucosamine has been shown to exert a protective effect against joint degradation and to enhance the synthesis of hyaluronan, the substance that give the joint fluid its thick viscosity, providing lubrication between the synovial membrane and cartilage.

Numerous double-blind studies have shown that Glucosamine is able to reduce pain associated with degenerative joint disease, often as well as or better than NSAIDs (non-steroidal anti-inflammatory drugs).